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Product Description

Product name: Ondansetron

CAS No.: 99614-02-5

Molecular formula: C18H19N3O

Molecular weight: 293.36

Melting point: 231-232°

It is a serotonin (5-HT3) receptor antagonist, a highly effective antiemetic, with high strength and high selectivity, which can control the vomiting caused by the stimulation of the receptors in the small intestine and CTZ (chemoreceptor activation center) . It is used for the treatment of emesis caused by chemotherapy and radiotherapy, especially the emesis induced by cisplatin, dacarbazine, nitrogen mustard, doxorubicin, etc. There is no outer cone effect, and it can be used with acetylcholine at the same time. The antiemetic effect is better than that of metoclopramide, Dompesidone, phenothiazine and butyryl benzene.

Application

1. It is used to prevent and treat nausea and vomiting caused by chemotherapy and radiotherapy, especially the anticancer drug cisplatin has a significant effect on vomiting.
 

2. It has been reported in the literature that it can also be used to prevent and treat nausea and vomiting caused by surgery.