Factory Supply Kpv(α-MSH (11-13) (free Acid) Peptide with Best Price CAS NO.67727-97-3

Wuhan Senwayer century chemical Co..Ltd located in the predominant Wuhan City where is a traffic hinge of China, specialize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and other places.

Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.

We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

1. Basic Information

2. Product Introduction
KPV is a tripeptide (i.e. 3 amino acids long) that makes up the C-terminal end of a larger naturally occurring melanocortin peptide hormone in your body known as alpha-melanocyte-stimulating hormone (α-MSH). Human body consists of various endogenous peptide hormones that are vital for the key body functions and overall development and wellbeing. One such group of hormones is called melanocyte stimulating hormones or melanotropins. These hormones are primarily responsible for hair and skin pigmentation, maintain optimal energy levels in the body, play key role in sexual activity and help protect against inflammation.Out of this class of melanotropin hormones, the most important hormones are alpha melanocyte stimulating hormones (a-MSH). a-MSH is an endogenous peptide hormone, composed of 13 amino acids, and is responsible for metabolic activities, sexual behavior and skin pigmentation.Over time, with the help of continuous research on a-MSH hormones, scientists were able to isolate a fragment of this protein hormone and identify its biological effects, especially its anti-inflammatory properties. This fragment is known as KPV peptide.

3. Biological Effects of KPV
KPV peptide has demonstrated various advantages in the therapeutic field, including:

• Inhibits intestinal inflammation
• Use as an anti-inflammatory agent
• Possess antipyretic properties
• Helps in the healing of wounds
• Prevents formation of hypertrophic scars
• Increased body mass
• Does not cause skin pigmentation, as opposed to its originating molecule a-MSH hormone

4. Product Side Effects

Clinical trials with KPV are yet to be conducted to fully demonstrate the potential of the peptide in the human body.
However, as with other peptides, some common side effects may include:

• Pain, redness, and itchiness at the site of peptide injection
• Overdose may lead to water retention and swelling
• Dry mouth
• Dizziness
• High blood pressure
• Pain in joints
• Weight gain

5. KPV versus a-MSH

Continuous research between the two compounds have shown that while the peptide is an analogue of the hormone, there are certain differences between the two, which should be taken into consideration depending on the intended use:

a-MSH, the intact molecule, is the more potent molecule amongst the two. However, it has a serious drawback - excessive skin pigmentation - which is not seen in the case of the peptide. Furthermore, the peptide is remarkably easy to manufacture, thus making it less costly than the other compound.

a-MSH exerts its anti-inflammatory effects by binding with melanocortin receptors, including MC3 and MC4 receptors. The peptide does not bind to these MC3/4 receptors, but only to specific melanocortin receptors (such as MC1R). Thus, the mechanism of action of the two also differs.

Lastly, the peptide is more versatile in terms of administration - it can be easily administered via injections (either centrally or peripherally) through subcutaneous and intraperitoneal route, and can also be given orally. Latest research also shows that the peptide may be administered transdermally. This vast range of administrations suggest that the peptide will be more convenient for the patients to intake in the future.