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Product Description

Product name: Caffeic acid

CAS No.: 331-39-5

Molecular formula: C9H8O4

Molecular weight: 180.16

Melting point: 211-213 °C (dec.)(lit.)

Function

1. Antibacterial and antiviral: It has a wide range of antibacterial effects, but it can be inactivated by protein in the body. In vitro tests have shown that it has antiviral activity and has a strong inhibitory effect on vaccinia and adenovirus, followed by polio type I and parainfluenza type III viruses.
 

2. Anti-venom: Caffeic acid can completely inhibit 20 micrograms of rattlesnake venom phosphodiesterase at a dose of 3 micrograms, and is used as an antivenom.
 

3. Other effects: When taken orally or intraperitoneally, caffeic acid can improve the central excitability of rats; Orally, it can increase the secretion of hydrochloric acid in the human stomach, and can slow down the pulse; can enhance the tension of the uterus, this effect can be It is antagonized by papaverine, while atropine cannot. It can increase rat bile secretion. It has the effects of raising white blood cells, hemostasis and inactivating vitamin B1. It can inhibit the formation of lipid peroxide in mouse brain tissue homogenate. It has the effect of shortening blood clotting and bleeding time.
 

4. Toxicity: The LD50 of intraperitoneal injection in mice is 1583mg/kg; the intravenous injection in rabbits is 14mg/kg/day for ten consecutive days. There is no pathological change in the function of heart, liver, kidney and anatomical microscopy in rabbits.

Application

1. Intermediate of caffeic acid. Used in organic synthesis.

2. It can be used safely in cosmetics and has a wide range of antibacterial and antiviral activities. Can absorb ultraviolet light. A low concentration is an auxiliary agent that inhibits skin-type hair dyes, which is beneficial to enhance the strength of the color.