Wuhan Senwayer century chemical Co..Ltd located in the predominant Wuhan City where is a traffic hinge of China, specialize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and other places.

Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.

We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Product Introduction

Name: tianeptinesulfate

English synonym :tianeptinesulfate; (Thiazepin-11-ylAmino)HeptanoicAcidSemisulfateMonohydrateTianeptineSemisulfateMonohydrate; 7 - [(3 - Chloro - 6, 10 - dihydro - - methyl - 5, 5 - dioxidodibenzo [c, f] [1, 2] thiazepin - 11 - yl) amino] heptanoicacidsulfatehydrate (2:1:2); Tianeptinehemisulfatemonohydrate(THM); 7 - [(3-6 - methyl - Chloro - 5, 5 - dioxido - 6, 11 - dihydrodibenzo [c, f] [1, 2] thiazepin - 11 - yl) amino] heptanoicacidsulfatehydrate (2:1:2); Tianeptinehemisulfatehydrate; Thiazepin-11-ylAmino)HeptanoicAcidSemisulfate; THM

CAS no. : 1224690-84-9

Molecular formula: C42H56Cl2N4O14S3

Molecular weight: 1008.01344

Product Function

Its elimination half-life is 2.5 to 3 hours. The elimination half-life has been found to be increased to 4 to 9 hours in the elderly. The drug has an active metabolite, with a much longer elimination half-life. Tianeptine is excreted 65% in the urine and 15% in feces. depression research has formulated several key goals for the development of novel therapeutics, including faster onset of antidepressant effects, efficacy in treatment-resistant subjects and minimization of side effects.1 The atypical antidepressant tianeptine (Figure 1a), an agent with established clinical efficacy, already addresses several limitations of standard antidepressants.2 Namely, it shows fast effects against some depressive symptoms (cognitive and anxiety symptoms), is effective in patients resistant to selective serotonin reuptake inhibitor therapy3 and shows a better side effect profile compared with selective serotonin reuptake inhibitors and tricyclic antidepressants.2 Interestingly, unlike other tricyclic antidepressants, tianeptine does not inhibit biogenic amine transporters, and despite longstanding interest in this agent, its direct target, and thus its molecular mechanism of action, have remained elusiv.