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Product Description

Product name:  Olanzapine

CAS No.: 132539-06-1

Molecular formula: C17H20N4S

Molecular weight: 312.43

Melting point: 195°C

Olanzapine is a new atypical neuroleptic drug that can bind to dopamine receptors, 5-HT receptors and cholinergic receptors, and has an antagonistic effect. Antagonizing the D2 receptor is related to the treatment of positive symptoms of schizophrenia; antagonizing the 5-HT2A receptor is related to the treatment of negative symptoms of schizophrenia. Unlike clozapine, this product does not cause agranulocytosis, and there is no delayed-onset disorder and severe symptoms of neurosis. Oral absorption is good, food has no effect on its absorption rate, and the peak plasma concentration can be reached 5 to 8 hours after oral administration. Mainly metabolized in the liver, about 75% of this product is excreted in the urine in the form of metabolites.

Application

It is suitable for the acute phase and maintenance treatment of schizophrenia and other mental illnesses with severe positive and/or negative symptoms; it can also relieve the common secondary affective symptoms of schizophrenia and related diseases.